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Pathophysiology of compartment syndrome

Pathophysiology of Compartment Syndrom

The pathophysiology of compartment syndrome is based on the arteriovenous gradient theory. The high pressure within the compartment leads to a decrease in the arteriovenous gradient, to a lowering of tissue PO2 and finally to a metabolic deficit Acute compartment syndrome (ACS) is a surgical emergency warranting prompt evaluation and treatment. It can occur with any elevation in interstitial pressure in a closed osseo-fascial compartment [Pathophysiology of the compartment syndrome]. [Article in German] Tscherne H, Echtermeyer V, Oestern HJ. PMID: 6715175 [Indexed for MEDLINE] Publication Types: English Abstract; MeSH terms. Adolescent; Adult; Aged; Child; Compartment Syndromes/physiopathology* Extracellular Space/physiology; Female; Humans; Intracellular Fluid/physiology; Mal

Donaldson, J., Haddad, B., & Khan, W. (June 27, 2014). The Pathophysiology, Diagnosis and Current Management of Acute Compartment Syndrome. The Open Orthapaedics Journal. Volume 8, pg 185-193. doi: 10.2174/187432500140801085 Kam, J.L., Hu, M., Peiler, L.L., & Yamamoto, L.G. (July, 2003). Acute Compartment Syndrome Signs and Symptoms Described i Download. Compartment syndrome: pathophysiology. Pramod Kumar. There is general agreement that raised compartment pressure beyond certain level and time leads to vascular injury to the various structures (muscle, nerves) in the compartment. Various mechanisms producing this are spasm, critical closing phenomenon and alteration in arteriole. Acute compartment syndrome (ACS) is a surgical emergency warranting prompt evaluation and treatment. It can occur with any elevation in interstitial pressure in a closed osseo-fascial compartment. Resultant ischaemic damage may be irreversible within six hours and can result in long-term morbidity and even death Focus on Compartment Syndrome; Published: 22 November 2007; Epidemiology, Etiology, Pathophysiology and Diagnosis of the Acute Compartment Syndrome of the Extremity. Heinrich M. J. Janzing MD, PhD 1,2 European Journal of Trauma and Emergency Surgery volume 33, pages 576-583 (2007)Cite this articl

Pathophysiology and mechanisms of compartment syndrom

pathophysiology of Compartment Syndrome. Please at the minimal of 8 to 10 sentences. Nathan F. Biology. 3 days, 7 hours ago. pathophysiology of Compartment Syndrome. Please at the minimal of 8 to 10 sentences. Video Player is loading. Play Video PATHOPHYSIOLOGY AND DIAGNOSIS OF CHRONIC COMPARTMENT SYNDROME ROBERT A. PEDOWITZ, MD, PhD, and DAVID H. GERSHUNI, MD, FRCS Chronic compartment syndrome (CCS) should be considered in the differential diagnosis of exertional leg pain. Currently, the pathophysiology of CCS and the mechanisms of pain production are not completely understood The Pathophysiology, Diagnosis and Current Management of Acute Compartment Syndrome James Donaldson, Behrooz Haddad, Wasim S Khan Open Orthop J. 2014; 8: 185-193

Chronic compartment syndrome (CCS) is a recurrent syndrome during exercise or work. CCS is characterized by pain and disability that subside when the precipitating activity is stopped but that.. The pathophysiology, classification, and etiologies of acute extremity compartment syndrome are reviewed here. The clinical features, diagnosis, and treatment of acute extremity compartment syndrome, including fasciotomy techniques and management following fasciotomy, are reviewed elsewhere. Chronic compartment syndromes are reviewed separately

Chronic compartment syndrome (CCS) should be considered in the differential diagnosis of exertional leg pain. Currently, the pathophysiology of CCS and the mechanisms of pain production are not completely understood. It may be difficult to differentiate CCS from other etiologies of leg pain based on the history and physical examination The most widely accepted hypothesis for the pathophysiology of acute extremity compartment syndrome is the arteriovenous pressure gradient theory . The increased compartment pressure restricts local tissue perfusion by reducing the arteriovenous pressure gradient (reduced arterial pressure, increased venous pressure) and, if prolonged, will result in cellular anoxia leading to damage to nerve and muscle tissues [ 3 ] IAP was found to be elevated in the few cases of OHSS in which it was measured, substantiating the conclusion that OHSS may be considered a compartment syndrome. An understanding of the pathophysiology of increased intrabdominal pressure is useful in the management of OHSS

(PDF) Pathophysiology and mechanisms of compartment syndrom

PATHOPHYSIOLOGY. Compartment syndrome is defined as a symptom complex resulting from increased tissue pressure within a limited space that compromises the circulation and function of the contents of that space. This occurs when intramuscular pressure is elevated to a level and for a period of time sufficient to reduce capillary perfusion Abdominal compartment syndrome is a potentially lethal condition caused by any event that produces intra-abdominal hypertension; the most common cause is blunt abdominal trauma. Increasing intra-abdominal pressure causes progressive hypoperfusion and ischemia of the intestines and other peritoneal and retroperitoneal structures Compartment syndrome: pathophysiology, clinical presentations, treatment, and prevention in human and veterinary medicine. Lindsey K. Nielsen DVM, Search for more papers by this author. To review the human and veterinary literature pertaining to all forms of compartment syndrome (CS) Compartment syndrome is defined as a critical pressure increase within a confined compartmental space. Any fascial compartment can be affected. The most common sites affected are in the leg, thigh, forearm, foot, hand and buttock.. In this article, we shall look at the pathophysiology, clinical features and management of acute compartment syndrome

Intra-abdominal hypertension, the presence of elevated intra-abdominal pressure, and abdominal compartment syndrome, the development of pressure-induced organ-dysfunction and failure, have been increasingly recognized over the past decade as causes of significant morbidity and mortality among critically ill surgical and medical patients. Elevated intra-abdominal pressure can cause. The pathophysiology of acute extremity compartment syndrome involves external compression or internal expansion within the compartment leading to increased tissue pressure, reduced capillary blood flow, tissue hypoxia and necrosis

Overview Pathophysiology: An increased pressure within a space that can only hold so much pressure causes a compromise in the circulation. The tissue in the space will become ischemic and nerve damage will occur. Compartment syndrome Fluid build up compartments Limbs Abdomen Needs emergent treatment Nursing Points General Injury occurs Physical Anabolic steroid use Fluid [ Comprehensively addressing the topic of the compartment syndrome, this book covers all aspects of this painful and complex condition, ranging from the history to the pathophysiology and treatment in the various body compartments affected by the syndrome, as well as the short- and long-term outcomes The pathophysiology behind acute compartment syndrome is generally ignored by treating physicians. Pressure and subjective signs like pain have been used as surrogate measures of pathology. The pathophysiology of compartment syndrome is based on the arteriovenous gradient theory. The high pressure within the compartment leads to a decrease in the arteriovenous gradient, to a lowering of tissue PO2 and finally to a metabolic deficit. The tolerance of increased pressure by nerve and muscle is defined by the relationship of mean. Pathophysiology of Compartment Syndrome. Skeletal muscle groups are covered by a tough, relatively inflexible membrane called fascia. It is a sheet of connective tissue beneath the skin that attaches, stabilizes, encloses, and separates muscles and other internal organs. (1) This separation forms parallel tunnels within the length of the.

Video: Pathophysiology of Compartment Syndrome SpringerLin

The Pathophysiology of Compartment Syndrome : Techniques

Unlike acute compartment syndrome, which usually results from trauma, the pathophysiology of CECS is not well understood.CECS may result from ischemic changes within the compartment; however, multiple theories and mechanisms have been suggested (see Pathophysiology and Etiology) Compartment pressure monitoring using a STIC pressure monitor can aid in the diagnosis of compartment syndrome with a delta pressure of 30 mmHg or below suggestive of acute compartment syndrome. The definitive, or recommended, treatment is prompt surgical decompression of all the involved compartments. Time to diagnosis is critical 1. Compartment syndrome is associated with serious long-term morbidity. 2. Appropriate treatment is invasive and involves its own risks. 3. The presentation of compartment syndrome is variable. 4. The diagnosis of compartment syndrome relies largely on clinical findings. 5.Pressure monitoring may provide supplemental but imperfect diagnostic.

The pathophysiology of the acute compartment syndrom

Compartment syndrome is a painful condition, with muscle pressure reaching dangerous levels. Acute compartment syndrome is a medical emergency, usually caused by trauma, like a car accident or broken bone. Chronic (or exertional) compartment syndrome is caused by intense, repetitive exercise and usually stops with rest or changes in routine Compartment Syndrome Evaluation. Review Box 54-1 Compartment syndrome evaluation: indications, contraindications, complications, and equipment. Open fractures, dislocations, and exposed joints are true orthopedic emergencies that must be managed aggressively to prevent morbidity and mortality. Even when managed appropriately, these injuries may. Shelby Resnick, Lewis J. Kaplan, in Critical Care Nephrology (Third Edition), 2019. Abstract. Abdominal compartment syndrome is an evolving and complex entity affecting those with and without surgical disease. Advances in the understanding of the underlying pathophysiology have allowed improved recognition of the downstream sequelae of rising intraabdominal pressure and identification of.

[Compartment syndrome

  1. Acute orbital compartment syndrome (AOCS) is a rare but treatable complication of increased pressure within the confined orbital space. It typically results from facial trauma or a surgical procedure, but many medical conditions have been known to cause AOCS (see Etiology). AOCS must be promptly diagnosed. If left untreated, patients with AOCS.
  2. Intramuscular pressures with limb compression clarification of the pathogenesis of the drug-induced muscle-compartment syndrome. N Engl J Med . 1979 May 24. 300(21):1169-72. [Medline]
  3. extremity compartment syndrome.14 Pathophysiology The major muscle groups and neurovascular structures in the extremities are separated into compartments by dense connective tissue called fascia. The biomechanical functions of fascia are providing attachment sites fo
  4. Image: Schmidt, OTA core curriculum presentation acute compartment syndrome 2018. C. ore. C. urriculum. V5. PATHOPHYSIOLOGY • In damaged tissue, rising pressure reduction in flow to muscle • Reduction in flow tissue ischemia • Tissue ischemia More cellular injury and release of osmotically active cellular contents into interstitial flui
  5. Pathophysiology. Acute compartment syndrome is the result of an increased pressure in a closed, relatively inelastic osteofascial compartment . There is then a spiralling action that results in a rapid increase in pressure requiring early action (Fig. 1) . The increasing pressure reduces the capillary and venous blood flow, and the resulting.
  6. Pathophysiology. Acute compartment syndrome occurs due to decreased intracompartmental space or increased intracompartmental fluid volume because the surrounding fascia is inherently non-compliant. As the compartment pressure increases, hemodynamics are impaired. There is normally an equilibrium between venous outflow and arterial inflow
  7. A Compartment Syndrome (CS) exists when the increased pressure in a closed anatomic space threatens the viability of surrounding tissue. Within the body there are 4 compartments, the head, the chest, the abdomen and the extremities. Within each compartment; an individual organ or a region with multiple organs can develop a CS

(PDF) The Pathophysiology, Diagnosis and Current

[Pathophysiology of the compartment syndrome]

PATHOPHYSIOLOGY — Multiple explanations for the complex pathophysiology of acute compartment syndrome (ACS) exist. These are discussed in greater detail separately (see Pathophysiology, classification, and causes of acute extremity compartment syndrome). In all cases, the final common pathway is cellular anoxia due to local ischemia - compartment syndrome of the lower extremity: Clarification of the pathogenesis of the drug-induced muscle-compartment syndrome. A practical approach to compartmental syndromes. Part II. Diagnosis. Well-limb compartment syndrome after prolonged lateral decubitus positioning. A report of two cases Although the exact pathophysiology of acute compartment syndrome is still debated, 3 the most commonly accepted theory is the arteriovenous pressure gradient theory. 4 In this theory, the rise in intracompartment pressure increases venous pressure, which in turn reduces the arteriovenous pressure gradient, reducing local tissue perfusion. The. Pathophysiology. Compartment syndrome is defined as 'an increased pressure within a confined compartmental space decreasing the perfusion pressure to the tissue. CS is caused by increasing pressure due to the edema and/or hemorrhage within an anatomic compartment bound. Increased pressures leads to the decreased capillary perfusion pressure. Pathophysiology and management of abdominal compartment syndrome From American Journal of Critical Care, 7/1/03 by Jeffrey Walker. Abdominal compartment syndrome is a potentially lethal condition caused by any event that produces intra-abdominal hypertension; the most common cause is blunt abdominal trauma

Compartment syndrome

Pathophysiology Compartment syndrome occurs when the tissue pressure within a closed osteo-fascial muscle compartment rises above a level required to maintain blood flow through the capillaries and into the venous drainage system. Normal tissue pressure is 0-10 mm Hg. The capillary filling pressure is essentially diastolic arterial pressure Compartment syndrome (CS) is a condition in which the perfusion pressure falls below the tissue pressure in a closed anatomic space, with subsequent compromise of circulation and function of the tissues. Each muscle and muscle group is enclosed in a compartment bound by rigid walls of bone and fascia. Pathophysiology:. What is a compartment syndrome? intra comp. pressure (35-40 mmhg) capillaries collapse Blood flow to muscles and nerves Bl.Vs collapse 5. Pathophysiology: Increased compartment pressure leads to increased venous pressure which decreases A-V gradient resulting in muscle and nerve ischemia. 6 The compartment syndrome occurs due to a severely painful condition within an enclosed bundle of muscle in lower or upper extremities or other parts of the body due to pressure build-up. Although.

Key Points • Compartment syndrome is defined as an elevation of the interstitial pressure in a closed osseo-fascial compartment that results in microvascular compromise. • High suspicion is. What is Compartment Syndrome? Limb muscles are contained in a fibrous sheath known as a compartment. If blood leaks into the compartment, or the compartment is compressed, this can cause a decrease in neurovascular integrity, distal to the compressing agent or injury. This is known as compartment syndrome (Wedro 2016) Pathophysiology. Compartment syndrome is defined as a condition in which a closed compartment's pressure increases to such an extent that the microcirculation of the tissues in that compartment is diminished . Two factors are responsible for this condition, either a decrease in a compartment volume or an increase in the contents of a. Compartment syndrome is a self-perpetuating cascade of events. It begins with the tissue edema that normally occurs after injury (eg, because of soft-tissue swelling or a hematoma). If edema develops within a closed fascial compartment, typically in the anterior or posterior compartments of the leg, there is little room for tissue expansion, so.

Compartment Syndrome in children. An increased need for analgesics is often the first sign of CS in children and should be considered a significant sign for ongoing tissue necrosis. CS remains a clinical diagnosis and compartment pressure should be measured only as a confirmatory test in non-communicative patients or when the diagnosis is unclear Editor, Thank you for giving me the opportunity to answer the letter by Killer et al. (2011).. Recently, an article discussing the possibility of a compartment syndrome within the lamina cribrosa as a possible pathogenic factor in glaucoma has been published ().Typically, a compartment syndrome describes the compression of tissue, nerves and blood vessels inside a closed space (compartment. Chronic exertional compartment syndrome is most frequently encountered among long-distance runners. Pathophysiology. Elevated interstitial pressure in a closed osteofascial compartment may be secondary to several different factors. Hemorrhage within the compartment or direct trauma to the muscles with subsequent edema can lead to increased.

Pathophysiology. Compartment syndrome is a condition that results from increased pressure within the fascial layers that the muscles are grouped into--the compartments after which the syndrome is named.Generally, a compartment consists of the muscles that perform a specific action and their associated nerves/vessels Compartment Syndrome Pathophysiology Normal tissue pressure 0-4 mm Hg 8-10 with exertion Absolute pressure theory 30 mm Hg - Mubarak 45 mm Hg - Matsen Pressure gradient theory < 20 mm Hg of diastolic pressure - Whitesides McQueen, et al 23 Pathogenesis blood flow is blocked when the tissue pressure exceeds the perfusion pressure within a fixed-volume compartment; this results in a lack of oxygen and the accumulation of waste products, causing pain and decreased peripheral sensation irreversible tissue damage occurs between 6-8 hours after onse PATHOPHYSIOLOGY. ACS is defined as 'a critical pressure increase within a confined compartmental space causing a decline in the perfusion pressure to the tissue within that compartment' [3-6].It can occur with any elevation in interstitial pressure within an osseo-fascial compartment What is Exertional Compartment Syndrome? Exertional compartment syndrome (ECS) is a type of compartment syndrome. Compartment syndrome occurs when the pressure in the muscles builds up to high and causes disturbances in blood flow to the muscles and nerves. Another type of compartment syndrome is acute compartment, which is most often caused by.

Compartment syndrome is a serious condition that occurs when there's a large amount of pressure inside a muscle compartment. Compartments are groups of muscle tissue, blood vessels, and nerves. Results from increased interstitial pressure in closed osteofascial compartments. Can be caused by fracture, compartment haemorrhage, direct soft-tissue injury, or direct muscular injury. High index of suspicion and early recognition are crucial. Intracompartmental pressures >30 to 40 mmHg or wit.. Compartment syndrome is a condition in which increased pressure within a muscle compartment (containing nerves and vasculature, enclosed by unyielding fascia) leads to impaired tissue perfusion. It most commonly affects the lower legs, but can also occur in other parts of the extremities or the abdomen This open access book describes the state of the art in the diagnosis and management of compartment syndrome. Pathophysiology, pressure management, fasciotomy of the upper and lower extremity, and treating unique populations are discussed in detail. A unique and timely resource for orthopedic and trauma surgeons. see more benefits. Buy this book

(PDF) Compartment syndrome: pathophysiology Pramod Kumar

  1. Acute compartment syndrome occurs when the tissue pressure within a closed muscle compartment exceeds the perfusion pressure and results in muscle and nerve ischemia. It typically occurs subsequent to a traumatic event, most commonly a fracture
  2. Acute compartment syndrome is a devastating condition caused by raised pressure within a facial compartment leading to decreased perfusion with risk of irreversible muscle and nerve damage. Epidemiology. • Trauma (fractures 69%3, crush injuries, burns, contusions, gunshot wounds) • External compression (tight casts & dressings
  3. pathophysiology of muscular compartment syndrome that were described in the middle of the 19th century, the physiological mechanisms of the ACS were only proposed at the end of 19th and beginning of the 20th century 6. Nowadays, the ACS is well described entity which im-portance in various clinical conditions was recognized in the last two decades

The Pathophysiology, Diagnosis and Current Management of

Each compartment contains muscles, nerves and blood vessels. As you can see from this pictures below, there are 4 separate osteofascial compartments in the lower leg. Often, all 4 are affected by compartment syndrome of the leg. Compartments in other limbs Similar to the leg, such muscle compartments exist in other limbs such as Compartment syndrome (CS) is one of the true surgical emergencies in orthopaedic trauma, and the sequelae of a missed diagnosis can have serious implications. The development of a CS begins at the microvascular level with disruption of the homeostatic environment between venous pressure, arterial flow, and intracompartmental tissue pressure tingling or burning in the skin. numbness and paralysis. Chronic compartment syndrome symptoms: pain or cramping during exercise that stops once the activity stops. difficulty moving your foot. a muscle bulge big enough to see. A compartment is a group of muscles, nerves and blood vessels in the arm or leg Acute compartment syndrome (ACS) is a potentially serious complication following a tibia fracture. The rates of ACS with tibia fractures ranges from 2% to 9%. 1-3 Compartment syndrome occurs where there is excessive swelling within a closed fascia-bone space. The elevated pressure causes a decrease in capillary blood flow due to a decrease in. Chronic exertional compartment syndrome (CECS) is a reversible form of ACS triggered by physical activity. Symptoms typically resolve quickly once exercise is terminated. As CECS is an episodic condition and compartment tissues are normal at rest, some refer to the condition simply as exertional compartment syndrome

Acute compartment syndrome caused by a traumatic injury such as a fracture requires immediate treatment. If you experience severe muscle pain, numbness or tingling, a feeling of tightness in or around the muscle, or notice a pale or shiny skin tone around the affected area, NYU Langone doctors recommend that you go to the nearest emergency room immediately Chronic Compartment Syndrome • Stress Test -Serial Compartment Pressure • Resting >15mm Hg • 5 min post-ex. >25mm Hg » Rydholm et al CORR 1983 -Volumetrics -Nerve conduction Velocities » Pedowitz et al. JHS 1988 71. Chronic Compartment Syndrome • Treatment - Modification of activity - Splinting - Elective Fasciotomy 72 Europe PMC is an archive of life sciences journal literature. In an experimental study in dogs of the anterior tibial compartment syndrome, three measurements were taken before, during, and following raising pressure in the compartment: blood flow, muscle function, and peroneal nerve conduction Although compartment syndrome is well recognized to occur in the extremities, it also occurs in the abdomen and, some believe, in the intracranial cavity. Compartment syndrome occurs when a fixed compartment, defined by myofascial elements or bone, becomes subject to increased pressure, leading to ischemia and organ dysfunction

Epidemiology, Etiology, Pathophysiology and Diagnosis of

Pathophysiology Compartment syndrome is caused by an elevation of pressure within a fibro-osseous space resulting in de-creased tissue perfusion. The initial rise in intracompartmental pressure causes increased extravascular ve-nous pressure. Because of lack of musculature in the wall media, thi -This is a limb-saving procedure when used to treat acute compartment syndrome-Also called surgical decompression. Nursing 101 - Compartment Syndrome-Early recognition via regular neurovascular assessments-Notify of pain unrelieved by drugs and out of proportion to injur of compartment syndrome in this group.16 However, pain may be an unreliable symptom as it is subjective and vari-able. It may be absent in established acute compartment syndrome associated with nerve injury, or minimal in deep posterior compartment syndrome.35 The signs of compart-ment syndrome are tense, swollen compartments, pain o

What is the pathophysiology of acute compartment syndrome

Compartment syndrome of the lower leg is a devastating condition that frequently leads to permanent muscle and nerve damage, which may be associated with lifelong disability. The muscles of the lower leg live in four compartments, regions of muscles enclosed by thick, fibrous sheaths. After a trauma such as a broken bone or a crush injury. A fracture is the most frequent cause of acute compartment syndrome, with tibia fractures being the most common 1,2; Soft-tissue injury without fracture and forearm fractures are the second and third most common causes, respectively 2. Up to 30% of cases occur without evidence of fracture 3; Other causes include: vascular injury, burns, prolonged limb compression, crush injuries, drug overdose. It hurts when I run. That's what many orthopedic surgeons hear when runners and other athletes come into their offices. Sometimes people have obvious problem.. Answer: Compartment Syndrome 1-6. Pathophysiology: Compartment syndrome occurs secondary to ischemic injury from increased pressure within a confined tissue space. Etiologies include (list not all encompassing): burns, crush injuries, electrocution, trauma (fracture/hematoma), IV infiltration, reperfusion injury, prolonged malposition, physical activity (exertional compartment syndrome), and.

Acute compartment syndrome is a serious condition requiring immediate medical care. A lack of urgent medical treatment can result in serious complications such as loss of function and even amputation. While the pathophysiology of acute compartment syndrome is well understood, numerous potential causes are still being discovered. A rare cause of acute compartment syndrome is IV infiltration For over a century, there have been medical descriptions of compartment syndrome. In 1881, Volkmann [3] first described the clinical findings of myonecrosis and contracture due to prolonged muscle. With compartment syndrome, compartment refers to separate sections of the body that contain muscles, nerves, and blood vessels surrounded by a layer of fibrous connective tissue, called fascia. When the pressure within these compartments rises, normal blood flow can be cut off, leading to tissue damage due to hypoxia , or the lack of oxygen The pathophysiology of CECS is not completely understood, but it is certainly different from the more familiar acute compartment syndrome. Rather than through abrupt injury, the pressure within the compart-ment involved rises upon exercise of the extremity and related muscles. The pathophysiology could possibly be

Compartment Syndrome: Causes, Diagnosis, Symptoms, and

Compartment Syndrome = elevated interstitial pressure in a closed fascial compartment (P>30 mmHg) Compartment P > capillary perfusion pressure Pressure relative to diastolic <20-30mmHg consider faciotomy Vascular compromise, myoneural damage, tissue hypoxi Flaccid paralysis is a neurological condition characterized by weakness or paralysis and reduced muscle tone without other obvious cause (e.g., trauma). This abnormal condition may be caused by disease or by trauma affecting the nerves associated with the involved muscles. For example, if the somatic nerves to a skeletal muscle are severed, then the muscle will exhibit flaccid paralysis

Compartment syndrome - AO Foundatio

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